Biology and Geology

 

Michael J. Bumbulis, Ph.D.

Dr. Bumbulis earned his M.S. from The Ohio State University in Zoology and his Ph.D. from Case Western Reserve University in Genetics.   He teaches Genetics, Molecular Biology, Anatomy & Physiology, Principles of Neuroscience and Senior Biology Seminar, along with special topics courses on cell biology.  His research focus is two-fold.  First, as an extension of his Ph. D thesis work, he is genetically dissecting Transcription Factor IIIA to determine which positions are crucial for protein stability. Secondly, since being at Baldwin Wallace University, he has become interested in detecting and characterizing programmed cell death in single-celled organisms. 

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Grant Support and Publications:

Publications:

Setzer DR, Schulman DB, Gunther CV, Bumbulis MJ.  2009. Use of a reporter gene assay in yeast for genetic analysis of DNA-protein interactions.  Methods Mol Biol. 2009;543:219-41.
 
Brady KL, Ponnampalam SN, Bumbulis MJ, Setzer DR.  2005. Mutations in TFIIIA that increase stability of the TFIIIA-5 S rRNA gene complex: unusual effects on the kinetics of complex assembly and dissociation. J Biol Chem. 2005 Jul 22;280(29):26743-50.

Genetic analysis of DNA-protein interactions using a reporter gene assay in yeast. Setzer DR, Schulman DB, Bumbulis MJ.  2001. Genetic analysis of DNA-protein interactions using a reporter gene assay in yeast. Methods Mol Biol. 2001;148:431-49.
 
Faculty-Student Collaborative Scholarship:
 
Balog, B. and Bumbulis, M.J. Apoptosis-like process observed in golden brown algae: Monochrysis lutheri. Spring Science Poster Session 2009.  Baldwin Wallace University, Berea, Ohio.  April 2009.
 
Kerci, A. and Bumbulis, M.J. Hydrogen peroxide induces apoptosis in Tetrahymena pyriformis. Spring Science Poster Session 2009.  Baldwin Wallace University, Berea, Ohio.  April 2009.
 
Platt, S. and Bumbulis, M.J. Mutation of TFIIIA determines sequences important to tertiary structure and susceptibility to protein degradation.  Spring Science Poster Session 2009.  Baldwin Wallace University, Berea, Ohio.  April 2008.
 
Grant Support/Funding:
 
2010.  Reseach Costs Grant. Baldwin Wallace University. - $2800
 
2007.  Reseach Costs Grant. Baldwin Wallace University. - $2900
 
2005. Genomic Education Matching Funds (GEMF) grant from LI-COR Biosciences. -  $34,949.50 cost met with a $25,000 grant from the George W. Codrington Charitable Foundation.
 
2003.  Gund Student-Faculty Research Grant.  Baldwin Wallace University. - $2800
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